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What Happens to Most THC and CBD Oil in the Body?

Jane Summers



What Happens to Most THC and CBD Oil in the Body?

Cannabidiol, also known as CBD, has gained a great deal of popularity in the past year or two due to its potential therapeutic benefits. The substance comes in several forms as well and can be found in beverages in some countries. But, one of the main questions that arises, is whether CBD really has the positive impact that many claims that it has. Although there is no solid answer, at least this overview can provide some insight into what happens to most of the CBD and THC, the psychoactive substance in CBD that must be 0.3% or lower for the CBD product to be legal, once they enter the body.

The Bioavailability of CBD

Bioavailability refers to the degree and rate in which a substance absorbs into the bloodstream, and it impact the level of effect that the CBD user experiences. According to Medium, bioavailability can vary based on the type of consumption method and the level of CBD in the product that one is using. That is, weaker products with less CBD are likely to have a low bioavailability, while stronger products with a high level of CBD are more likely to have a high bioavailability.

Another way in which users can experience a higher bioavailability may be an oil-based product. As Anavii Market explains in a blog post, some products on the market feature CBD that has been emulsified in nanotechnology. The emulsification breaks down the CBD into tiny molecules, and such molecules pass through the cell membrane into the blood stream.

Delivery Method

Another quality that affects the amount of CBD and THC in the body is the type of delivery method that one uses. According to a post by Wisdom CBD, there are six primary delivery methods that can be used for CBD to enter the body, and they include:


Sublingual delivery is when a CBD product is placed beneath the tongue. Sublingual products can include tinctures, or oil extracts.


Topical delivery is a where product that is applied to the skin’s surface and thus absorbs into the body. Topical delivery can be achieved with creams, salves, and the like.


Transdermal delivery is similar to topical in that it is also a product that is applied to the skin. The topical delivery usually comes in the form of a patch. When the patch is applied to the skin’s surface, the CBD releases and penetrates past the cell membrane and into the body.


Inhalant delivery is where one inhales smoke that contains CBD and THC. This is perhaps the most common delivery method.


Oral delivery is where one ingests CBD through a pill or capsule.

According to Wisdom CBD, the delivery method that provides the highest amount of bioavailability was an inhalant. Keep in mind that there was no data for topical delivery. The method that came close to an inhalant is a sublingual, and then oral/ingestion.

In addition to looking at the types of bioavailability methods, there are other considerations to take into account that can impact bioavailability. For example, those who are looking to enhance bioavailability may want to consume foods with a high amount of fat when taking CBD. This may mimic the impact that oil-based products have. Thus, if all you have on hand are products that are not dissolved in oil, this option may be effective. Further, even though the amount of CBD that one takes can impact bioavailability, the effective amount may vary from person to person. Users should determine what the best amount is for them and their needs.


Overall, those who are looking to enhance the effectiveness of the products that they take may want to consider the formula’s bioavailability and the types of products that they use. It may also be beneficial to determine what the right amount of CBD is one’s needs.

Jane is a regular contributor who learned about the great benefits of CBD a few years ago after starting it herself. Impressed by its effects, she's interested in helping others learn about options that can be helpful for them.

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